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A phenolic ester from Aglaia loheri leaves reveals cytotoxicity towards sensitive and multidrug-resistant cancer cells

BACKGROUND: Bioactivity-guided fractionation of extracts of Aglaia loheri Blanco (Meliaceae) yielded a cytotoxic isolate, termed Maldi 531.2[M + H](+). This phenolic ester was further investigated for its in vitro cytotoxicity toward human CCRF-CEM leukemia cells and their multi-drug resistant (MDR)...

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Detalles Bibliográficos
Autores principales: Dapat, Else, Jacinto, Sonia, Efferth, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816152/
https://www.ncbi.nlm.nih.gov/pubmed/24160768
http://dx.doi.org/10.1186/1472-6882-13-286