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Knockdown of RON receptor kinase delays but does not prevent tumor progression while enhancing HGF/MET signaling in pancreatic cancer cell lines

In this study, the role of RON (receptor originated from nantes) in tumor progression was further investigated in context with MET expression and activity. RON and MET expressions were not detected in an immortalized normal human pancreas cell line (HPNE), but were co-expressed in five of seven panc...

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Detalles Bibliográficos
Autores principales: Zhao, S, Cao, L, Freeman, J W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816215/
https://www.ncbi.nlm.nih.gov/pubmed/24100611
http://dx.doi.org/10.1038/oncsis.2013.36