Cargando…
T antigen transformation reveals Tp53/RB-dependent route to PLAC1 transcription activation in primary fibroblasts
PLAC1 (placenta-specific 1) is a gene that is placenta specific and transcribed very little, if at all, in any somatic tissue. It is nevertheless expressed in many cancer cell lines. To understand how cancer cells may activate the gene in nonexpressing cells, we found that a model is provided by cla...
Autores principales: | Chen, Y, Schlessinger, D, Nagaraja, R |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816221/ https://www.ncbi.nlm.nih.gov/pubmed/23999628 http://dx.doi.org/10.1038/oncsis.2013.31 |
Ejemplares similares
-
A Pan-Cancer Assessment of RB1/TP53 Co-Mutations
por: Cai, Ling, et al.
Publicado: (2022) -
Unscheduled HDAC4 repressive activity in human fibroblasts triggers TP53‐dependent senescence and favors cell transformation
por: Paluvai, Harikrishnareddy, et al.
Publicado: (2018) -
Study of polymorphisms in the TP53 and RB1 genes in children with retinoblastoma in northern Mexico
por: Anaya-Pava, Edwin J., et al.
Publicado: (2017) -
Prevalence of TP-53/Rb-1 Co-Mutation in Large Cell Neuroendocrine Carcinoma
por: Saghaeiannejad Esfahani, Hoda, et al.
Publicado: (2021) -
Multifaced roles of PLAC8 in cancer
por: Mao, Misha, et al.
Publicado: (2021)