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A novel orthotopic mouse model of head and neck cancer and lymph node metastasis

Prognosis of head and neck squamous cell carcinoma (HNSCC) is largely determined by the extent of lymph node (LN) metastasis at diagnosis, and this appears to be controlled by cancer cell genetics. To examine the role of these genes in LN metastasis, we created a human-in-mouse orthotopic model of H...

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Detalles Bibliográficos
Autores principales: Masood, R, Hochstim, C, Cervenka, B, Zu, S, Baniwal, S K, Patel, V, Kobielak, A, Sinha, U K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816223/
https://www.ncbi.nlm.nih.gov/pubmed/24018643
http://dx.doi.org/10.1038/oncsis.2013.33