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Centrosomal kinase Nek2 cooperates with oncogenic pathways to promote metastasis

Centrosomal kinase Nek2 is overexpressed in different cancers, yet how it contributes toward tumorigenesis remains poorly understood. dNek2 overexpression in a Drosophila melanogaster model led to upregulation of Drosophila Wnt ortholog wingless (Wg), and alteration of cell migration markers—Rho1, R...

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Detalles Bibliográficos
Autores principales: Das, T K, Dana, D, Paroly, S S, Perumal, S K, Singh, S, Jhun, H, Pendse, J, Cagan, R L, Talele, T T, Kumar, S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816224/
https://www.ncbi.nlm.nih.gov/pubmed/24018644
http://dx.doi.org/10.1038/oncsis.2013.34