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Centrosomal kinase Nek2 cooperates with oncogenic pathways to promote metastasis
Centrosomal kinase Nek2 is overexpressed in different cancers, yet how it contributes toward tumorigenesis remains poorly understood. dNek2 overexpression in a Drosophila melanogaster model led to upregulation of Drosophila Wnt ortholog wingless (Wg), and alteration of cell migration markers—Rho1, R...
Autores principales: | Das, T K, Dana, D, Paroly, S S, Perumal, S K, Singh, S, Jhun, H, Pendse, J, Cagan, R L, Talele, T T, Kumar, S |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816224/ https://www.ncbi.nlm.nih.gov/pubmed/24018644 http://dx.doi.org/10.1038/oncsis.2013.34 |
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