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Heterologous vaccination against human tuberculosis modulates antigen-specific CD4(+) T-cell function

Heterologous prime-boost strategies hold promise for vaccination against tuberculosis. However, the T-cell characteristics required for protection are not known. We proposed that boost vaccines should induce long-lived functional and phenotypic changes to T cells primed by Bacille Calmette Guerin (B...

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Detalles Bibliográficos
Autores principales: Dintwe, One B, Day, Cheryl L, Smit, Erica, Nemes, Elisa, Gray, Clive, Tameris, Michele, McShane, Helen, Mahomed, Hassan, Hanekom, Willem A, Scriba, Thomas J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wiley-VCH Verlag GmbH & Co 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816254/
https://www.ncbi.nlm.nih.gov/pubmed/23737382
http://dx.doi.org/10.1002/eji.201343454