Tyrosine kinases inhibition by Imatinib slows progression in chronic anti-thy1 glomerulosclerosis of the rat

BACKGROUND: Chronic progressive mesangioproliferative nephropathy represents a major cause of end-stage renal disease worldwide. Until now, effective approaches to stop or even slow its progression are limited. We tested the effects of an inhibitor of PDGF receptor, abl and c-kit tyrosine kinases, I...

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Detalles Bibliográficos
Autores principales: Wang-Rosenke, Yingrui, Khadzhynov, Dymtro, Loof, Tanja, Mika, Alice, Kawachi, Hiroshi, Neumayer, Hans-H, Peters, Harm
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816310/
https://www.ncbi.nlm.nih.gov/pubmed/24119229
http://dx.doi.org/10.1186/1471-2369-14-223

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816310/
https://www.ncbi.nlm.nih.gov/pubmed/24119229
http://dx.doi.org/10.1186/1471-2369-14-223

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