The site of allergen expression in hematopoietic cells determines the degree and quality of tolerance induced through molecular chimerism

The transplantation of allergens (e.g. Phl p 5 or Bet v 1) expressed on BM cells as membrane-anchored full-length proteins leads to permanent tolerance at the T-cell, B-cell, and effector-cell levels. Since the exposure of complete allergens bears the risk of inducing anaphylaxis, we investigated he...

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Detalles Bibliográficos
Autores principales: Baranyi, Ulrike, Gattringer, Martina, Farkas, Andreas M, Hock, Karin, Pilat, Nina, Iacomini, John, Valenta, Rudolf, Wekerle, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 2013
Materias:
Immunomodulation
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816328/
https://www.ncbi.nlm.nih.gov/pubmed/23765421
http://dx.doi.org/10.1002/eji.201243277

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816328/
https://www.ncbi.nlm.nih.gov/pubmed/23765421
http://dx.doi.org/10.1002/eji.201243277

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