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Up-regulation of Synaptotagmin IV within amyloid plaque-associated dystrophic neurons in Tg2576 mouse model of Alzheimer’s disease

AIM: To investigate the involvement of the vesicular membrane trafficking regulator Synaptotagmin IV (Syt IV) in Alzheimer’s disease pathogenesis and to define the cell types containing increased levels of Syt IV in the β-amyloid plaque vicinity. METHODS: Syt IV protein levels in wild type (WT) and...

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Detalles Bibliográficos
Autores principales: Tratnjek, Larisa, Živin, Marko, Glavan, Gordana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Croatian Medical Schools 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816566/
https://www.ncbi.nlm.nih.gov/pubmed/24170720
http://dx.doi.org/10.3325/cmj.2013.54.419