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Molecular Dynamics Simulations of Hsp90 with an Eye to Inhibitor Design
Proteins carry out their functions through interactions with different partners. Dynamic conformational switching among different structural sub-states favors the adaptation to the shapes of the different partners. Such conformational changes can be determined by diverse biochemical factors, such as...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816644/ https://www.ncbi.nlm.nih.gov/pubmed/24280699 http://dx.doi.org/10.3390/ph5090944 |