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Molecular Dynamics Simulations of Hsp90 with an Eye to Inhibitor Design

Proteins carry out their functions through interactions with different partners. Dynamic conformational switching among different structural sub-states favors the adaptation to the shapes of the different partners. Such conformational changes can be determined by diverse biochemical factors, such as...

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Detalles Bibliográficos
Autores principales: Moroni, Elisabetta, Morra, Giulia, Colombo, Giorgio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816644/
https://www.ncbi.nlm.nih.gov/pubmed/24280699
http://dx.doi.org/10.3390/ph5090944