Differential Cellular and Molecular Effects of Butyrate and Trichostatin A on Vascular Smooth Muscle Cells

The histone deacetylase (HDAC) inhibitors, butyrate and trichostatin A (TSA), are epigenetic histone modifiers and proliferation inhibitors by downregulating cyclin D1, a positive cell cycle regulator, and upregulating p21Cip1 and INK family of proteins, negative cell cycle regulators. Our recent st...

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Detalles Bibliográficos
Autores principales: Milton, Shirlette G., Mathew, Omana P., Yatsu, Frank M., Ranganna, Kasturi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816648/
https://www.ncbi.nlm.nih.gov/pubmed/24280698
http://dx.doi.org/10.3390/ph5090925

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816648/
https://www.ncbi.nlm.nih.gov/pubmed/24280698
http://dx.doi.org/10.3390/ph5090925

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