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A Review of Therapeutic Aptamer Conjugates with Emphasis on New Approaches
The potential to emulate or enhance antibodies with nucleic acid aptamers while lowering costs has prompted development of new aptamer-protein, siRNA, drug, and nanoparticle conjugates. Specific focal points of this review discuss DNA aptamers covalently bound at their 3' ends to various protei...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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MDPI
2013
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816688/ https://www.ncbi.nlm.nih.gov/pubmed/24276022 http://dx.doi.org/10.3390/ph6030340 |