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A Review of Therapeutic Aptamer Conjugates with Emphasis on New Approaches

The potential to emulate or enhance antibodies with nucleic acid aptamers while lowering costs has prompted development of new aptamer-protein, siRNA, drug, and nanoparticle conjugates. Specific focal points of this review discuss DNA aptamers covalently bound at their 3' ends to various protei...

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Detalles Bibliográficos
Autor principal: Bruno, John G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816688/
https://www.ncbi.nlm.nih.gov/pubmed/24276022
http://dx.doi.org/10.3390/ph6030340