Disease-Causing Allele-Specific Silencing by RNA Interference

Small double-stranded RNAs (dsRNAs) of approximately 21-nucleotides in size, referred to as small interfering RNA (siRNA) duplexes, can induce sequence-specific posttranscriptional gene silencing, or RNA interference (RNAi). Since chemically synthesized siRNA duplexes were found to induce RNAi in ma...

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Detalles Bibliográficos
Autor principal: Hohjoh, Hirohiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816697/
https://www.ncbi.nlm.nih.gov/pubmed/24276122
http://dx.doi.org/10.3390/ph6040522

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816697/
https://www.ncbi.nlm.nih.gov/pubmed/24276122
http://dx.doi.org/10.3390/ph6040522

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