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Disease-Causing Allele-Specific Silencing by RNA Interference

Small double-stranded RNAs (dsRNAs) of approximately 21-nucleotides in size, referred to as small interfering RNA (siRNA) duplexes, can induce sequence-specific posttranscriptional gene silencing, or RNA interference (RNAi). Since chemically synthesized siRNA duplexes were found to induce RNAi in ma...

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Detalles Bibliográficos
Autor principal:	Hohjoh, Hirohiko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2013
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816697/ https://www.ncbi.nlm.nih.gov/pubmed/24276122 http://dx.doi.org/10.3390/ph6040522

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