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An Allosteric Modulator of the Adenosine A(1) Receptor Improves Cardiac Function Following Ischaemia in Murine Isolated Hearts

The effect of an allosteric modulator of the adenosine A(1) receptors was investigated using an ischaemia-reperfusion protocol in murine isolated hearts. Isolated hearts were perfused with Kreb-Henseleit solution gassed with carbogen gas (95% O(2) and 5% CO(2)) in Langendorff mode and electrically p...

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Detalles Bibliográficos
Autores principales: Butcher, Anna, Scammells, Peter J., White, Paul J., Devine, Shane M., Rose’Meyer, Roselyn B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816699/
https://www.ncbi.nlm.nih.gov/pubmed/24276124
http://dx.doi.org/10.3390/ph6040546