Phorbol Ester Modulation of Ca(2+) Channels Mediates Nociceptive Transmission in Dorsal Horn Neurones

Phorbol esters are analogues of diacylglycerol which activate C1 domain proteins, such as protein kinase C (PKC). Phorbol ester/PKC pathways have been proposed as potential therapeutic targets for chronic pain states, potentially by phosphorylating proteins involved in nociception, such as voltage-d...

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Detalles Bibliográficos
Autores principales: Yang, Li, Topia, Iqbal, Schneider, Toni, Stephens, Gary J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Brief Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816730/
https://www.ncbi.nlm.nih.gov/pubmed/24276261
http://dx.doi.org/10.3390/ph6060777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3816730/
https://www.ncbi.nlm.nih.gov/pubmed/24276261
http://dx.doi.org/10.3390/ph6060777

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