An Anthelmintic Drug, Pyrvinium Pamoate, Thwarts Fibrosis and Ameliorates Myocardial Contractile Dysfunction in a Mouse Model of Myocardial Infarction

Metabolic adaptation to limited supplies of oxygen and nutrients plays a pivotal role in health and disease. Heart attack results from insufficient delivery of oxygen and nutrients to the heart, where cardiomyocytes die and cardiac fibroblasts proliferate – the latter causing scar formation, which i...

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Detalles Bibliográficos
Autores principales: Murakoshi, Motoaki, Saiki, Kyohei, Urayama, Kyoji, Sato, Thomas N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817040/
https://www.ncbi.nlm.nih.gov/pubmed/24223934
http://dx.doi.org/10.1371/journal.pone.0079374

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817040/
https://www.ncbi.nlm.nih.gov/pubmed/24223934
http://dx.doi.org/10.1371/journal.pone.0079374

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