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N-Alkylated Aminoacyl sulfamoyladenosines as Potential Inhibitors of Aminoacylation Reactions and Microcin C Analogues Containing D-Amino Acids

Microcin C analogues were recently envisaged as important compounds for the development of novel antibiotics. Two issues that may pose problems to these potential antibiotics are possible acquisition of resistance through acetylation and in vivo instability of the peptide chain. N-methylated aminoac...

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Detalles Bibliográficos
Autores principales: Vondenhoff, Gaston H., Pugach, Ksenia, Gadakh, Bharat, Carlier, Laurence, Rozenski, Jef, Froeyen, Mathy, Severinov, Konstantin, Van Aerschot, Arthur
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817062/
https://www.ncbi.nlm.nih.gov/pubmed/24223911
http://dx.doi.org/10.1371/journal.pone.0079234