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Variance Heterogeneity in Saccharomyces cerevisiae Expression Data: Trans-Regulation and Epistasis

Here, we describe the results from the first variance heterogeneity Genome Wide Association Study (VGWAS) on yeast expression data. Using this forward genetics approach, we show that the genetic regulation of gene-expression in the budding yeast, Saccharomyces cerevisiae, includes mechanisms that ca...

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Detalles Bibliográficos
Autores principales: Nelson, Ronald M., Pettersson, Mats E., Li, Xidan, Carlborg, Örjan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817098/
https://www.ncbi.nlm.nih.gov/pubmed/24223957
http://dx.doi.org/10.1371/journal.pone.0079507