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A New Synthetic FGF Receptor Antagonist Inhibits Arteriosclerosis in a Mouse Vein Graft Model and Atherosclerosis in Apolipoprotein E-Deficient Mice

OBJECTIVE: The role of fibroblast growth factors (FGFs) in the development of vascular diseases remains incompletely understood. The objective of this study was to examine the effects of a new small-molecule multi-FGF receptor blocker with allosteric properties, SSR128129E, on neointimal proliferati...

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Detalles Bibliográficos
Autores principales: Dol-Gleizes, Frédérique, Delesque-Touchard, Nathalie, Marès, Anne-Marie, Nestor, Anne-Laure, Schaeffer, Paul, Bono, Françoise
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817113/
https://www.ncbi.nlm.nih.gov/pubmed/24224032
http://dx.doi.org/10.1371/journal.pone.0080027