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Common Oncogenic Mutations Are Infrequent in Oral Squamous Cell Carcinoma of Asian Origin

OBJECTIVES: The frequency of common oncogenic mutations and TP53 was determined in Asian oral squamous cell carcinoma (OSCC). MATERIALS AND METHODS: The OncoCarta(™) panel v1.0 assay was used to characterize oncogenic mutations. In addition, exons 4-11 of the TP53 gene were sequenced. Statistical an...

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Detalles Bibliográficos
Autores principales: Zanaruddin, Sharifah Nurain Syed, Yee, Pei San, Hor, Seen Yii, Kong, Yink Heay, Ghani, Wan Maria Nabillah Wan Abd, Mustafa, Wan Mahadzir Wan, Zain, Rosnah Binti, Prime, Stephen S., Rahman, Zainal Ariff Abd, Cheong, Sok-Ching
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817115/
https://www.ncbi.nlm.nih.gov/pubmed/24224046
http://dx.doi.org/10.1371/journal.pone.0080229