The Scavenger Protein Apoptosis Inhibitor of Macrophages (AIM) Potentiates the Antimicrobial Response against Mycobacterium tuberculosis by Enhancing Autophagy

Apoptosis inhibitor of macrophages (AIM), a scavenger protein secreted by tissue macrophages, is transcriptionally regulated by the nuclear receptor Liver X Receptor (LXR) and Retinoid X Receptor (RXR) heterodimer. Given that LXR exerts a protective immune response against M. tuberculosis, here we a...

Descripción completa

Detalles Bibliográficos
Autores principales: Sanjurjo, Lucía, Amézaga, Núria, Vilaplana, Cristina, Cáceres, Neus, Marzo, Elena, Valeri, Marta, Cardona, Pere-Joan, Sarrias, Maria-Rosa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817138/
https://www.ncbi.nlm.nih.gov/pubmed/24223991
http://dx.doi.org/10.1371/journal.pone.0079670

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817138/
https://www.ncbi.nlm.nih.gov/pubmed/24223991
http://dx.doi.org/10.1371/journal.pone.0079670

Ejemplares similares