Cargando…

The 5′-3′ exoribonuclease Pacman (Xrn1) regulates expression of the heat shock protein Hsp67Bc and the microRNA miR-277–3p in Drosophila wing imaginal discs

Pacman/Xrn1 is a highly conserved exoribonuclease known to play a critical role in gene regulatory events such as control of mRNA stability, RNA interference and regulation via miRNAs. Although Pacman has been well studied in Drosophila tissue culture cells, the biologically relevant cellular pathwa...

Descripción completa

Detalles Bibliográficos
Autores principales: Jones, Christopher I, Grima, Dominic P, Waldron, Joseph A, Jones, Sue, Parker, Hannah N, Newbury, Sarah F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Landes Bioscience 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817156/
https://www.ncbi.nlm.nih.gov/pubmed/23792537
http://dx.doi.org/10.4161/rna.25354