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NF-κB Repressing Factor Inhibits Chemokine Synthesis by Peripheral Blood Mononuclear Cells and Alveolar Macrophages in Active Pulmonary Tuberculosis

NF-κB repressing factor (NRF) is a transcriptional silencer implicated in the basal silencing of specific NF-κB targeting genes, including iNOS, IFN-β and IL-8/CXCL8. IP-10/CXCL10 and IL-8/CXCL8 are involved in neutrophil and lymphocyte recruitment against M. tuberculosis (MTb) and disease progressi...

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Detalles Bibliográficos
Autores principales: Huang, Kuo-Hsiung, Wang, Chun-Hua, Lee, Kang-Yun, Lin, Shu-Min, Lin, Chien-Huang, Kuo, Han-Pin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817197/
https://www.ncbi.nlm.nih.gov/pubmed/24223729
http://dx.doi.org/10.1371/journal.pone.0077789