Mice with Chimeric Livers Are an Improved Model for Human Lipoprotein Metabolism

OBJECTIVE: Rodents are poor model for human hyperlipidemias because total cholesterol and low density lipoprotein levels are very low on a normal diet. Lipoprotein metabolism is primarily regulated by hepatocytes and we therefore assessed whether chimeric mice extensively repopulated with human cell...

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Detalles Bibliográficos
Autores principales: Ellis, Ewa C. S., Nauglers, Scott, Parini, Paolo, Mörk, Lisa-Mari, Jorns, Carl, Zemack, Helen, Sandblom, Anita Lövgren, Björkhem, Ingemar, Ericzon, Bo-Göran, Wilson, Elizabeth M., Strom, Stephen C., Grompe, Markus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817217/
https://www.ncbi.nlm.nih.gov/pubmed/24223822
http://dx.doi.org/10.1371/journal.pone.0078550

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817217/
https://www.ncbi.nlm.nih.gov/pubmed/24223822
http://dx.doi.org/10.1371/journal.pone.0078550

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