Polyphosphate-Mediated Inhibition of Tartrate-Resistant Acid Phosphatase and Suppression of Bone Resorption of Osteoclasts

Inorganic polyphosphate (poly(P)) has recently been found to play an important role in bone formation. In this study, we found that tartrate-resistant acid phosphatase (TRAP), which is abundantly expressed in osteoclasts, has polyphosphatase activity that degrades poly(P) and yields Pi as well as sh...

Descripción completa

Detalles Bibliográficos
Autores principales: Harada, Kana, Itoh, Hiromichi, Kawazoe, Yumi, Miyazaki, Shuichi, Doi, Kazuya, Kubo, Takayasu, Akagawa, Yasumasa, Shiba, Toshikazu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817253/
https://www.ncbi.nlm.nih.gov/pubmed/24223830
http://dx.doi.org/10.1371/journal.pone.0078612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817253/
https://www.ncbi.nlm.nih.gov/pubmed/24223830
http://dx.doi.org/10.1371/journal.pone.0078612

Ejemplares similares