Cargando…

Polyphosphate-Mediated Inhibition of Tartrate-Resistant Acid Phosphatase and Suppression of Bone Resorption of Osteoclasts

Inorganic polyphosphate (poly(P)) has recently been found to play an important role in bone formation. In this study, we found that tartrate-resistant acid phosphatase (TRAP), which is abundantly expressed in osteoclasts, has polyphosphatase activity that degrades poly(P) and yields Pi as well as sh...

Descripción completa

Detalles Bibliográficos
Autores principales:	Harada, Kana, Itoh, Hiromichi, Kawazoe, Yumi, Miyazaki, Shuichi, Doi, Kazuya, Kubo, Takayasu, Akagawa, Yasumasa, Shiba, Toshikazu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2013
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817253/ https://www.ncbi.nlm.nih.gov/pubmed/24223830 http://dx.doi.org/10.1371/journal.pone.0078612

Ejemplares similares

Inorganic Polyphosphate Suppresses Lipopolysaccharide-Induced Inducible Nitric Oxide Synthase (iNOS) Expression in Macrophages
por: Harada, Kana, et al.
Publicado: (2013)

Morphogenetic Study on the Maturation of Osteoblastic Cell as Induced by Inorganic Polyphosphate
por: Tsutsumi, Kaori, et al.
Publicado: (2014)

Activation of the FGF signaling pathway and subsequent induction of mesenchymal stem cell differentiation by inorganic polyphosphate
por: Kawazoe, Yumi, et al.
Publicado: (2008)

Osteoclasts secrete osteopontin into resorption lacunae during bone resorption
por: Luukkonen, Jani, et al.
Publicado: (2019)

Microcracks and Osteoclast Resorption Activity In Vitro
por: Rumpler, Monika, et al.
Publicado: (2012)

Optimization of the tartrate-resistant acid phosphatase detection by histochemical method
por: Galvão, M.J., et al.
Publicado: (2011)

The effects of seeding density and osteoclastic supplement concentration on osteoclastic differentiation and resorption
por: Remmers, Stefan J.A., et al.
Publicado: (2022)

Serum Bone Resorption Markers after Parathyroidectomy for Renal Hyperparathyroidism: Correlation Analyses for the Cross-Linked N-telopeptide of Collagen I and Tartrate-Resistant Acid Phosphatase
por: Hung, Kuo-Chin, et al.
Publicado: (2012)

Bone Alkaline Phosphatase and Tartrate-Resistant Acid Phosphatase: Potential Co-regulators of Bone Mineralization
por: Halling Linder, Cecilia, et al.
Publicado: (2017)

Monomeric Tartrate Resistant Acid Phosphatase Induces Insulin Sensitive Obesity
por: Lång, Pernilla, et al.
Publicado: (2008)

Role of tartrate-resistant acid phosphatase (TRAP) in long bone development
por: Blumer, Michael J.F., et al.
Publicado: (2012)

Effects of ibandronate-hydroxyapatite on resorptive activity of osteoclasts
por: Zhang, Xiaohui, et al.
Publicado: (2011)

Septins are critical regulators of osteoclastic bone resorption
por: Møller, Anaïs M. J., et al.
Publicado: (2018)

Rab GTPases in Osteoclastic Bone Resorption and Autophagy
por: Roy, Michèle, et al.
Publicado: (2020)

Modeling and simulation of bone mineral density in Japanese osteoporosis patients treated with zoledronic acid using tartrate-resistant acid phosphatase 5b, a bone resorption marker
por: Mori, Y., et al.
Publicado: (2018)

Osteoclasts and the resorption of bone by transplanted mammary carcinoma in rats.
por: O'Grady, R. L., et al.
Publicado: (1985)

Osteoclastic bone resorption directly activates osteoblast function
por: Udagawa, Nobuyuki
Publicado: (2012)

Osteoclast-independent bone resorption by fibroblast-like cells
por: Pap, Thomas, et al.
Publicado: (2003)

Hypoxic regulation of osteoclast differentiation and bone resorption activity
por: Knowles, Helen J
Publicado: (2015)

Dual effects of baicalin on osteoclast differentiation and bone resorption
por: Lu, Xuanyuan, et al.
Publicado: (2018)

The Role of Autophagy in Osteoclast Differentiation and Bone Resorption Function
por: Montaseri, Azadeh, et al.
Publicado: (2020)

Human osteoclast formation and resorptive function on biomineralized collagen
por: de Melo Pereira, Daniel, et al.
Publicado: (2021)

Identification of a non-purple tartrate-resistant acid phosphatase: an evolutionary link to Ser/Thr protein phosphatases?
por: Hadler, Kieran S, et al.
Publicado: (2008)

Expansion and Functional Divergence of Inositol Polyphosphate 5-Phosphatases in Angiosperms
por: Zhang, Zaibao, et al.
Publicado: (2019)

Influence of Implant Surface Topography on Primary Stability in a Standardized Osteoporosis Rabbit Model Study
por: Oue, Hiroshi, et al.
Publicado: (2015)

Tartrate-resistant acid phosphatase 5b is a marker of osteoclast number and volume in RAW 264.7 cells treated with receptor-activated nuclear κB ligand
por: LV, YUANDONG, et al.
Publicado: (2015)

Targeted Overexpression of Osteoactivin in Cells of Osteoclastic Lineage Promotes Osteoclastic Resorption and Bone Loss in Mice
por: Sheng, Matilda H.-C., et al.
Publicado: (2012)

Alterations in osteoclast function and phenotype induced by different inhibitors of bone resorption - implications for osteoclast quality
por: Neutzsky-Wulff, Anita V, et al.
Publicado: (2010)

Increased Tartrate-Resistant Acid Phosphatase Expression in Osteoblasts and Osteocytes in Experimental Osteoporosis in Rats
por: Solberg, Lene B., et al.
Publicado: (2014)

Association of Tartrate-Resistant Acid Phosphatase-Expressed Macrophages and Metastatic Breast Cancer Progression
por: Chen, Yu-Guang, et al.
Publicado: (2015)

Anti-Obesity Effect of Ginkgo Vinegar, a Fermented Product of Ginkgo Seed Coat, in Mice Fed a High-Fat Diet and 3T3-L1 Preadipocyte Cells
por: Hosoda, Shugo, et al.
Publicado: (2020)

Polyphosphoinositides-dependent regulation of the osteoclast actin cytoskeleton and bone resorption
por: Biswas, Rajat S, et al.
Publicado: (2004)

Ghrelin is an Osteoblast Mitogen and Increases Osteoclastic Bone Resorption In Vitro
por: Costa, Jessica L., et al.
Publicado: (2011)

HIV-1 tat and rev upregulates osteoclast bone resorption
por: Chew, Nicholas, et al.
Publicado: (2014)

Bone Remodeling and the Role of TRAF3 in Osteoclastic Bone Resorption
por: Boyce, Brendan F., et al.
Publicado: (2018)

Osteocyte-Related Cytokines Regulate Osteoclast Formation and Bone Resorption
por: Kitaura, Hideki, et al.
Publicado: (2020)

Aging and menopause reprogram osteoclast precursors for aggressive bone resorption
por: Møller, Anaïs Marie Julie, et al.
Publicado: (2020)

Finely-Tuned Calcium Oscillations in Osteoclast Differentiation and Bone Resorption
por: Okada, Hiroyuki, et al.
Publicado: (2020)

Development of Implant/Interconnected Porous Hydroxyapatite Complex as New Concept Graft Material
por: Doi, Kazuya, et al.
Publicado: (2012)

Flupentixol tartrate
por: Yamuna, Thammarse S., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_ftl9adfscr899uu0nnj5mujqdm