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A Novel Translocation Involving RUNX1 and HOXA Gene Clusters in a Case of Acute Myeloid Leukemia with t(7;21)(p15;q22)

Translocations involving chromosome 21q22 are frequently observed in hematologic malignancies including acute myeloid leukemia (AML), most of which have been known to be involved in malignant transformation through transcriptional dysregulation of Runt-related transcription factor 1 (RUNX1) target g...

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Detalles Bibliográficos
Autores principales: Moon, Yeonsook, Horsman, Douglas E., Humphries, R. Keith, Park, Gyeongsin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Association of Immunologists 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817305/
https://www.ncbi.nlm.nih.gov/pubmed/24198749
http://dx.doi.org/10.4110/in.2013.13.5.222