CXCR3/CCR5 pathways in metastatic melanoma patients treated with adoptive therapy and interleukin-2

BACKGROUND: Adoptive therapy with tumour-infiltrating lymphocytes (TILs) induces durable complete responses (CR) in ∼20% of patients with metastatic melanoma. The recruitment of T cells through CXCR3/CCR5 chemokine ligands is critical for immune-mediated rejection. We postulated that polymorphisms a...

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Detalles Bibliográficos
Autores principales: Bedognetti, D, Spivey, T L, Zhao, Y, Uccellini, L, Tomei, S, Dudley, M E, Ascierto, M L, De Giorgi, V, Liu, Q, Delogu, L G, Sommariva, M, Sertoli, M R, Simon, R, Wang, E, Rosenberg, S A, Marincola, F M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817317/
https://www.ncbi.nlm.nih.gov/pubmed/24129241
http://dx.doi.org/10.1038/bjc.2013.557

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817317/
https://www.ncbi.nlm.nih.gov/pubmed/24129241
http://dx.doi.org/10.1038/bjc.2013.557

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