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Aurora kinase A (AURKA) expression in colorectal cancer liver metastasis is associated with poor prognosis

BACKGROUND: Five-year survival after resection of colorectal cancer liver metastasis (CRLCM) is <30%. We recently found that aurora kinase A (AURKA) drives 20q gain-associated tumour progression and is associated with disease recurrence. This study evaluates the prognostic value of AURKA expressi...

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Detalles Bibliográficos
Autores principales: Goos, J A C M, Coupe, V M H, Diosdado, B, Delis-Van Diemen, P M, Karga, C, Beliën, J A M, Carvalho, B, van den Tol, M P, Verheul, H M W, Geldof, A A, Meijer, G A, Hoekstra, O S, Fijneman, R J A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817339/
https://www.ncbi.nlm.nih.gov/pubmed/24104968
http://dx.doi.org/10.1038/bjc.2013.608