Transcriptional Reprogramming of CD11b(+)Esam(hi) Dendritic Cell Identity and Function by Loss of Runx3

Classical dendritic cells (cDC) are specialized antigen-presenting cells mediating immunity and tolerance. cDC cell-lineage decisions are largely controlled by transcriptional factor regulatory cascades. Using an in vivo cell-specific targeting of Runx3 at various stages of DC lineage development we...

Descripción completa

Detalles Bibliográficos
Autores principales: Dicken, Joseph, Mildner, Alexander, Leshkowitz, Dena, Touw, Ivo P., Hantisteanu, Shay, Jung, Steffen, Groner, Yoram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817345/
https://www.ncbi.nlm.nih.gov/pubmed/24204843
http://dx.doi.org/10.1371/journal.pone.0077490

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817345/
https://www.ncbi.nlm.nih.gov/pubmed/24204843
http://dx.doi.org/10.1371/journal.pone.0077490

Ejemplares similares