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Transcriptional Reprogramming of CD11b(+)Esam(hi) Dendritic Cell Identity and Function by Loss of Runx3
Classical dendritic cells (cDC) are specialized antigen-presenting cells mediating immunity and tolerance. cDC cell-lineage decisions are largely controlled by transcriptional factor regulatory cascades. Using an in vivo cell-specific targeting of Runx3 at various stages of DC lineage development we...
Autores principales: | Dicken, Joseph, Mildner, Alexander, Leshkowitz, Dena, Touw, Ivo P., Hantisteanu, Shay, Jung, Steffen, Groner, Yoram |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817345/ https://www.ncbi.nlm.nih.gov/pubmed/24204843 http://dx.doi.org/10.1371/journal.pone.0077490 |
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