ER stress in rodent islets of Langerhans is concomitant with obesity and β-cell compensation but not with β-cell dysfunction and diabetes

OBJECTIVE: The objective of this study was to determine whether ER stress correlates with β-cell dysfunction in obesity-associated diabetes. METHODS: Quantitative RT-PCR and western blot analysis were used to investigate changes in the expression of markers of ER stress, the unfolded protein respons...

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Detalles Bibliográficos
Autores principales: Omikorede, O, Qi, C, Gorman, T, Chapman, P, Yu, A, Smith, D M, Herbert, T P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817349/
https://www.ncbi.nlm.nih.gov/pubmed/24145577
http://dx.doi.org/10.1038/nutd.2013.35

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817349/
https://www.ncbi.nlm.nih.gov/pubmed/24145577
http://dx.doi.org/10.1038/nutd.2013.35

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