Human disease locus discovery and mapping to molecular pathways through phylogenetic profiling

Genes with common profiles of the presence and absence in disparate genomes tend to function in the same pathway. By mapping all human genes into about 1000 clusters of genes with similar patterns of conservation across eukaryotic phylogeny, we determined that sets of genes associated with particula...

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Detalles Bibliográficos
Autores principales: Tabach, Yuval, Golan, Tamar, Hernández-Hernández, Abrahan, Messer, Arielle R, Fukuda, Tomoyuki, Kouznetsova, Anna, Liu, Jian-Guo, Lilienthal, Ingrid, Levy, Carmit, Ruvkun, Gary
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817400/
https://www.ncbi.nlm.nih.gov/pubmed/24084807
http://dx.doi.org/10.1038/msb.2013.50

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817400/
https://www.ncbi.nlm.nih.gov/pubmed/24084807
http://dx.doi.org/10.1038/msb.2013.50

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