Design of orthogonal genetic switches based on a crosstalk map of σs, anti-σs, and promoters

Cells react to their environment through gene regulatory networks. Network integrity requires minimization of undesired crosstalk between their biomolecules. Similar constraints also limit the use of regulators when building synthetic circuits for engineering applications. Here, we mapped the promot...

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Detalles Bibliográficos
Autores principales: Rhodius, Virgil A, Segall-Shapiro, Thomas H, Sharon, Brian D, Ghodasara, Amar, Orlova, Ekaterina, Tabakh, Hannah, Burkhardt, David H, Clancy, Kevin, Peterson, Todd C, Gross, Carol A, Voigt, Christopher A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: European Molecular Biology Organization 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817407/
https://www.ncbi.nlm.nih.gov/pubmed/24169405
http://dx.doi.org/10.1038/msb.2013.58

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817407/
https://www.ncbi.nlm.nih.gov/pubmed/24169405
http://dx.doi.org/10.1038/msb.2013.58

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