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Design of orthogonal genetic switches based on a crosstalk map of σs, anti-σs, and promoters
Cells react to their environment through gene regulatory networks. Network integrity requires minimization of undesired crosstalk between their biomolecules. Similar constraints also limit the use of regulators when building synthetic circuits for engineering applications. Here, we mapped the promot...
| Autores principales: | , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
European Molecular Biology Organization
2013
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817407/ https://www.ncbi.nlm.nih.gov/pubmed/24169405 http://dx.doi.org/10.1038/msb.2013.58 |