Cargando…

Flexible synthesis of anthracycline aglycone mimics via domino carbopalladation reactions

A synthesis of anthracycline aglycone derivatives is described. The key step utilizes a powerful domino carbopalladation approach and subsequent ring closure. During this process two of the four rings of the anthracycline scaffold are formed. Differently substituted carbohydrates and dialkyne chains...

Descripción completa

Detalles Bibliográficos
Autores principales: Leibeling, Markus, Werz, Daniel B
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817477/
https://www.ncbi.nlm.nih.gov/pubmed/24204433
http://dx.doi.org/10.3762/bjoc.9.258