Synthesis of enantiomerically pure N-(2,3-dihydroxypropyl)arylamides via oxidative esterification

A highly efficient synthesis of enantiomerically pure (S) and (R)-isomers of N-(2,3-dihydroxypropyl)arylamides has been developed with good overall yields in a two step process. The key step involves the ring opening of the chiral epoxide with a nitrogen heterocyclic carbene (NHC) and further rearra...

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Detalles Bibliográficos
Autores principales: Raghunadh, Akula, More, Satish S, Chaitanya, T Krishna, Kumar, Yadla Sateesh, Meruva, Suresh Babu, Rao, L Vaikunta, Kumar, U K Syam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2013
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817507/
https://www.ncbi.nlm.nih.gov/pubmed/24204425
http://dx.doi.org/10.3762/bjoc.9.250

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817507/
https://www.ncbi.nlm.nih.gov/pubmed/24204425
http://dx.doi.org/10.3762/bjoc.9.250

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