Post-Ugi gold-catalyzed diastereoselective domino cyclization for the synthesis of diversely substituted spiroindolines

An Ugi four-component reaction of propargylamine with 3-formylindole and various acids and isonitriles produces adducts which are subjected to a cationic gold-catalyzed diastereoselective domino cyclization to furnish diversely substituted spiroindolines. All the reactions run via an exo-dig attack...

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Detalles Bibliográficos
Autores principales: Kumar, Amit, Vachhani, Dipak D, Modha, Sachin G, Sharma, Sunil K, Parmar, Virinder S, Van der Eycken, Erik V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2013
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817510/
https://www.ncbi.nlm.nih.gov/pubmed/24204421
http://dx.doi.org/10.3762/bjoc.9.246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817510/
https://www.ncbi.nlm.nih.gov/pubmed/24204421
http://dx.doi.org/10.3762/bjoc.9.246

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