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Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition
Although the function of DNA methylation in gene promoter regions is well established in transcriptional repression, the function of the evolutionarily conserved widespread distribution of DNA methylation in gene body regions remains incompletely understood. Here, we show that DNA methylation is enr...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817542/ https://www.ncbi.nlm.nih.gov/pubmed/23938295 http://dx.doi.org/10.1038/cr.2013.110 |