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Intragenic DNA methylation modulates alternative splicing by recruiting MeCP2 to promote exon recognition

Although the function of DNA methylation in gene promoter regions is well established in transcriptional repression, the function of the evolutionarily conserved widespread distribution of DNA methylation in gene body regions remains incompletely understood. Here, we show that DNA methylation is enr...

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Detalles Bibliográficos
Autores principales: Maunakea, Alika K, Chepelev, Iouri, Cui, Kairong, Zhao, Keji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817542/
https://www.ncbi.nlm.nih.gov/pubmed/23938295
http://dx.doi.org/10.1038/cr.2013.110