Synthesis of enones, pyrazolines and pyrrolines with gem-difluoroalkyl side chains

Starting from easily accessible gem-difluoropropargylic derivatives, a DBU-mediated isomerisation affords enones in fair yields with a gem-difluoroalkyl chain. These derivatives were used to prepare pyrazolines and pyrrolines with the desired gem-difluoroalkyl side chain by cyclocondensations in goo...

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Detalles Bibliográficos
Autores principales: El Dine, Assaad Nasr, Khalaf, Ali, Grée, Danielle, Tasseau, Olivier, Fares, Fares, Jaber, Nada, Lesot, Philippe, Hachem, Ali, Grée, René
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2013
Materias:
Letter
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817575/
https://www.ncbi.nlm.nih.gov/pubmed/24204405
http://dx.doi.org/10.3762/bjoc.9.230

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817575/
https://www.ncbi.nlm.nih.gov/pubmed/24204405
http://dx.doi.org/10.3762/bjoc.9.230

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