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Statistical distributions of test statistics used for quantitative trait association mapping in structured populations

BACKGROUND: Spurious associations between single nucleotide polymorphisms and phenotypes are a major issue in genome-wide association studies and have led to underestimation of type 1 error rate and overestimation of the number of quantitative trait loci found. Many authors have investigated the inf...

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Detalles Bibliográficos
Autores principales: Teyssèdre, Simon, Elsen, Jean-Michel, Ricard, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817592/
https://www.ncbi.nlm.nih.gov/pubmed/23146127
http://dx.doi.org/10.1186/1297-9686-44-32