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Statistical distributions of test statistics used for quantitative trait association mapping in structured populations
BACKGROUND: Spurious associations between single nucleotide polymorphisms and phenotypes are a major issue in genome-wide association studies and have led to underestimation of type 1 error rate and overestimation of the number of quantitative trait loci found. Many authors have investigated the inf...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817592/ https://www.ncbi.nlm.nih.gov/pubmed/23146127 http://dx.doi.org/10.1186/1297-9686-44-32 |