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Building a pseudo-atomic model of the anaphase-promoting complex

The anaphase-promoting complex (APC/C) is a large E3 ubiquitin ligase that regulates progression through specific stages of the cell cycle by coordinating the ubiquitin-dependent degradation of cell-cycle regulatory proteins. Depending on the species, the active form of the APC/C consists of 14–15 d...

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Detalles Bibliográficos
Autores principales: Kulkarni, Kiran, Zhang, Ziguo, Chang, Leifu, Yang, Jing, da Fonseca, Paula C. A., Barford, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817697/
https://www.ncbi.nlm.nih.gov/pubmed/24189235
http://dx.doi.org/10.1107/S0907444913018593