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Applications of molecular replacement to G protein-coupled receptors

G protein-coupled receptors (GPCRs) are a large class of integral membrane proteins involved in regulating virtually every aspect of human physiology. Despite their profound importance in human health and disease, structural information regarding GPCRs has been extremely limited until recently. With...

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Detalles Bibliográficos
Autores principales: Kruse, Andrew C., Manglik, Aashish, Kobilka, Brian K., Weis, William I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Union of Crystallography 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817703/
https://www.ncbi.nlm.nih.gov/pubmed/24189241
http://dx.doi.org/10.1107/S090744491301322X