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Applications of molecular replacement to G protein-coupled receptors
G protein-coupled receptors (GPCRs) are a large class of integral membrane proteins involved in regulating virtually every aspect of human physiology. Despite their profound importance in human health and disease, structural information regarding GPCRs has been extremely limited until recently. With...
Autores principales: | Kruse, Andrew C., Manglik, Aashish, Kobilka, Brian K., Weis, William I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
International Union of Crystallography
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817703/ https://www.ncbi.nlm.nih.gov/pubmed/24189241 http://dx.doi.org/10.1107/S090744491301322X |
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