Cargando…

Targeting Platelet Thrombin Receptor Signaling to Prevent Thrombosis

Platelets contribute fundamentally to ischemic heart disease, and antiplatelet therapy has been critical to reducing acute thrombotic complications of atherosclerotic disease. Thrombin, by acting on protease activated receptors (PAR), is one of the most potent platelet activators. PAR-1 antagonists...

Descripción completa

Detalles Bibliográficos
Autores principales: Wallace, Eric L., Smyth, Susan S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817733/
https://www.ncbi.nlm.nih.gov/pubmed/24276376
http://dx.doi.org/10.3390/ph6080915