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The architecture of Tetrahymena telomerase holoenzyme

Telomerase adds telomeric repeats to chromosome ends using an internal RNA template and specialized telomerase reverse transcriptase (TERT), thereby maintaining genome integrity. Little is known about the physical relationships among protein and RNA subunits within a biologically functional holoenzy...

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Detalles Bibliográficos
Autores principales: Jiang, Jiansen, Miracco, Edward J., Hong, Kyungah, Eckert, Barbara, Chan, Henry, Cash, Darian D., Min, Bosun, Zhou, Z. Hong, Collins, Kathleen, Feigon, Juli
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817743/
https://www.ncbi.nlm.nih.gov/pubmed/23552895
http://dx.doi.org/10.1038/nature12062