Cargando…

The architecture of Tetrahymena telomerase holoenzyme

Telomerase adds telomeric repeats to chromosome ends using an internal RNA template and specialized telomerase reverse transcriptase (TERT), thereby maintaining genome integrity. Little is known about the physical relationships among protein and RNA subunits within a biologically functional holoenzy...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jiang, Jiansen, Miracco, Edward J., Hong, Kyungah, Eckert, Barbara, Chan, Henry, Cash, Darian D., Min, Bosun, Zhou, Z. Hong, Collins, Kathleen, Feigon, Juli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2013
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817743/ https://www.ncbi.nlm.nih.gov/pubmed/23552895 http://dx.doi.org/10.1038/nature12062

Ejemplares similares

Structure and folding of the Tetrahymena telomerase RNA pseudoknot
por: Cash, Darian D., et al.
Publicado: (2017)

Structure of the Tetrahymena thermophila telomerase RNA helix II template boundary element
por: Richards, Rebecca J., et al.
Publicado: (2006)

Single-molecule imaging of telomerase reverse transcriptase in human telomerase holoenzyme and minimal RNP complexes
por: Wu, Robert Alexander, et al.
Publicado: (2015)

Tracing the path of DNA substrates in active Tetrahymena telomerase holoenzyme complexes: mapping of DNA contact sites in the RNA subunit
por: Goldin, Svetlana, et al.
Publicado: (2012)

Cryo-EM structure of substrate-bound human telomerase holoenzyme
por: Nguyen, Thi Hoang Duong, et al.
Publicado: (2018)

Structure and sequence elements of the CR4/5 domain of medaka telomerase RNA important for telomerase function
por: Kim, Nak-Kyoon, et al.
Publicado: (2014)

Effect of pseudouridylation on the structure and activity of the catalytically essential P6.1 hairpin in human telomerase RNA
por: Kim, Nak-Kyoon, et al.
Publicado: (2010)

Multiple DNA-binding sites in Tetrahymena telomerase
por: Finger, Sharon N., et al.
Publicado: (2008)

A new role for proteins subunits of RNase P: stabilization of the telomerase holoenzyme
por: Garcia, P. Daniela, et al.
Publicado: (2020)

An unanticipated architecture of the 750 kD holoenzyme of 3-methylcrotonyl-CoA carboxylase
por: Huang, Christine S., et al.
Publicado: (2011)

Structural Basis of Template Boundary Definition in Tetrahymena Telomerase
por: Jansson, Linnea I., et al.
Publicado: (2015)

HnRNP F/H associate with hTERC and telomerase holoenzyme to modulate telomerase function and promote cell proliferation
por: Xu, Chenzhong, et al.
Publicado: (2019)

Correction to: HnRNP F/H associate with hTERC and telomerase holoenzyme to modulate telomerase function and promote cell proliferation
por: Xu, Chenzhong, et al.
Publicado: (2021)

Molecular architecture of the glycogen- committed PP1/PTG holoenzyme
por: Semrau, Marta Stefania, et al.
Publicado: (2022)

Genome-Scale Analysis of Programmed DNA Elimination Sites in Tetrahymena thermophila
por: Fass, Joseph N., et al.
Publicado: (2011)

The DEAH-box RNA helicase RHAU binds an intramolecular RNA G-quadruplex in TERC and associates with telomerase holoenzyme
por: Lattmann, Simon, et al.
Publicado: (2011)

Back to the future of RNA structure
por: Feigon, Juli
Publicado: (2015)

The methyl phosphate capping enzyme Bmc1/Bin3 is a stable component of the fission yeast telomerase holoenzyme
por: Porat, Jennifer, et al.
Publicado: (2022)

Filamentous Aggregates Are Fragmented by the Proteasome Holoenzyme
por: Cliffe, Rachel, et al.
Publicado: (2019)

Domain Structures and Inter-Domain Interactions Defining the Holoenzyme Architecture of Archaeal D-Family DNA Polymerase
por: Matsui, Ikuo, et al.
Publicado: (2013)

Crystal structure of the α(6)β(6) holoenzyme of propionyl-coenzyme A carboxylase
por: Huang, Christine S., et al.
Publicado: (2010)

Organization of an Activator-Bound RNA Polymerase Holoenzyme
por: Bose, Daniel, et al.
Publicado: (2008)

Stepwise assembly of the human replicative polymerase holoenzyme
por: Hedglin, Mark, et al.
Publicado: (2013)

Structure of the processive human Pol δ holoenzyme
por: Lancey, Claudia, et al.
Publicado: (2020)

The DNA polymerase III holoenzyme contains γ and is not a trimeric polymerase
por: Dohrmann, Paul R., et al.
Publicado: (2016)

A human-Tetrahymena pseudoknot chimeric telomerase RNA reconstitutes a nonprocessive enzyme in vitro that is defective in telomere elongation
por: Marie-Egyptienne, Delphine T., et al.
Publicado: (2005)

hLARP7 C-terminal domain contains an xRRM that binds the 3′ hairpin of 7SK RNA
por: Eichhorn, Catherine D., et al.
Publicado: (2016)

The CaMKII holoenzyme structure in activation-competent conformations
por: Myers, Janette B., et al.
Publicado: (2017)

Transgenerational function of Tetrahymena Piwi protein Twi8p at distinctive noncoding RNA loci
por: Farley, Brian M., et al.
Publicado: (2017)

Structure and substrate selectivity of the 750-kDa α(6)β(6) holoenzyme of geranyl-CoA carboxylase
por: Jurado, Ashley R., et al.
Publicado: (2015)

Tetrahymena Comparative Genomics Database (TCGD): a community resource for Tetrahymena
por: Yang, Wentao, et al.
Publicado: (2019)

Several RNase T2 enzymes function in induced tRNA and rRNA turnover in the ciliate Tetrahymena
por: Andersen, Kasper L., et al.
Publicado: (2012)

Single Turnover Autophosphorylation Cycle of the PKA RIIβ Holoenzyme
por: Zhang, Ping, et al.
Publicado: (2015)

A distinct holoenzyme organization for two-subunit pyruvate carboxylase
por: Choi, Philip H., et al.
Publicado: (2016)

Cryo-electron microscopy structure of an archaeal ribonuclease P holoenzyme
por: Wan, Futang, et al.
Publicado: (2019)

Identification and characterization of a heterotrimeric archaeal DNA polymerase holoenzyme
por: Yan, Jiangyu, et al.
Publicado: (2017)

PP2A-B55 Holoenzyme Regulation and Cancer
por: Goguet-Rubio, Perrine, et al.
Publicado: (2020)

Comparison of Solution and Crystal Structures of PreQ(1) Riboswitch Reveals Calcium-Induced Changes in Conformation and Dynamics
por: Zhang, Qi, et al.
Publicado: (2011)

POLYRIBOSOMES FROM TETRAHYMENA
por: Hartman, H., et al.
Publicado: (1970)

Mutation accumulation in Tetrahymena
por: Brito, Patrícia H, et al.
Publicado: (2010)

Cannot write session to /tmp/vufind_sessions/sess_en1ceh7te5p7hq92aquhuqva2c