Alzheimer's disease-associated peptide Aβ(42) mobilizes ER Ca(2+) via InsP(3)R-dependent and -independent mechanisms

Dysregulation of Ca(2+) homeostasis is considered to contribute to the toxic action of the Alzheimer's disease (AD)-associated amyloid-β-peptide (Aβ). Ca(2+) fluxes across the plasma membrane and release from intracellular stores have both been reported to underlie the Ca(2+) fluxes induced by...

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Detalles Bibliográficos
Autores principales: Jensen, Laura E., Bultynck, Geert, Luyten, Tomas, Amijee, Hozeefa, Bootman, Martin D., Roderick, H. Llewelyn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2013
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817845/
https://www.ncbi.nlm.nih.gov/pubmed/24204331
http://dx.doi.org/10.3389/fnmol.2013.00036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3817845/
https://www.ncbi.nlm.nih.gov/pubmed/24204331
http://dx.doi.org/10.3389/fnmol.2013.00036

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